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Reading VCFs and Building Mutational-Spectrum Catalogs21 days ago
1. Load packages | 2. Locate test VCFs | 3. Read the SBS VCF | 4. Split into SBS / DBS / ID sub-tables | 5. Annotate the SBS rows | 6. Build SBS catalogs | 7. Plot SBS catalogs | 8. Build and plot ID catalogs | 9. Counts ↔ density | 10. Collapse from finer to coarser resolutions | 11. Catalog I/O | See also
Plotting mutational signatures with mSigPlot3 months ago
Introduction | SBS96 -- single base substitutions in trinucleotide context | Optional styling: horizontal gridlines and an external title | ID83 -- COSMIC indel classification | ID89 -- 89-channel indel classification | ID476 -- 476-channel indel classification | ID476 right panel | DBS78 -- doublet base substitutions | SBS192 -- SBS with transcription strand | DBS144 -- DBS with transcription strand | DBS136 -- DBS heatmap | SBS1536 -- SBS pentanucleotide context | SBS288 -- SBS with three-strand context | ID166 -- indel genic/intergenic | SBS12 -- strand bias summary | Auto-dispatch with plot_guess() | Multi-sample PDF export
Reading VCFs and Building Mutational-Spectrum Catalogs5 months ago
1. Load packages | 2. Locate test VCFs | 3. Read the SBS VCF | 4. Split into SBS / DBS / ID sub-tables | 5. Annotate the SBS rows | 6. Build SBS catalogs | 7. Plot SBS catalogs | 8. Build and plot ID catalogs | 9. Counts ↔ density | 10. Collapse from finer to coarser resolutions | 11. Catalog I/O | See also